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Managing Cancer Care

List of Biosimilars Used in Cancer Treatment

A biologic is a medicine that is made in a living system, such as yeast, bacteria, or animal cells. A biosimilar is a medicine that is very close in structure and function to a specific biologic medicine (also known as the reference product). The biosimilar has a structure that is highly similar to, but not exactly the same as, the brand name biologic. A biosimilar behaves in much the same way, so that there are "no meaningful differences" between it and the original biologic. To learn more, see What Are Biosimilar Drugs?

Biosimilars used in cancer treatment

For some brand name biologics used in the treatment of cancer, one or more biosimilars are now approved for use by the US Food and Drug Administration (FDA).

Biosimilars for the biologic medicine bevacizumab (Avastin):

  • Mvasi
  • Zirabev
  • Alymsys
  • Vegzelma
  • Avzivi

Biosimilars for the biologic medicine rituximab (Rituxan):

  • Truxima
  • Ruxience
  • Riabni

Biosimilars for the biologic medicine trastuzumab (Herceptin):

  • Ogivri
  • Herzuma
  • Ontruzant
  • Trazimera
  • Kanjinti

Biosimilars for the biologic medicine filgrastim (Neupogen):

  • Zarxio
  • Nivestym
  • Releuko

Biosimilars for the biologic medicine pegfilgrastim (Neulasta):

  • Fulphila
  • Udenyca
  • Ziextenzo
  • Nyvepria
  • Fylnetra
  • Stimufend

Biosimilar for the biologic medicine epoetin alfa (Epogen):

  • Retacrit

The American Cancer Society medical and editorial content team

Our team is made up of doctors and oncology certified nurses with deep knowledge of cancer care as well as journalists, editors, and translators with extensive experience in medical writing.

US Food and Drug Administration. Biosimilar Product Information. 2022. Accessed at on May 31, 2022.

Last Revised: December 8, 2023

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