The American Cancer Society (ACS) helps people with breast cancer in every community. Our research programs have played a role in many of the prevention, screening, and treatment advances that save lives from breast cancer today. And, we continue to fund research to help save even more lives in the future.
“I still have moments when it hits me that despite my work in this area, numerous talks I’ve given, and access to care on rare cancer, a rare cancer went undetected in my family, and another rare cancer was barely detected on time."
—Gayanthri R. Devi, PhD, Duke University School of Medicine
The ACS Cancer Prevention Studies have played a role in identifying or validating every known common genetic variant for breast, prostate, and pancreatic cancers. We've collaborated with scientists across the United States to analyze large compilations of data. We're helping make discoveries about the genetics of cancer that have the potential to improve screening guidelines, lead to new targeted therapies, and inform follow-up care after cancer treatment."
Genes that are vulnerable to cancer-causing changes (mutations), which are sometimes inherited from a parent. Several dozen cancer-predisposition genes have been identified, and about 5% to 10% of all cancers result directly from those inherited.
For example, BRCA1 and BRCA2 are inherited cancer predisposition genes, and mutations on them increase the risk of developing certain cancers, including breast, ovarian, and prostate.
Read on to learn more about the findings of this study.
The ACS funds scientists who conduct research about breast cancer at medical schools, universities, research institutes, and hospitals throughout the United States. We use a rigorous and independent peer review process to select the most innovative research projects proposals to fund.
The grant statistics to the left are as of August 1, 2023.
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