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Cancer Risk and Prevention

Lifetime Risk of Developing or Dying From Cancer

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The lifetime risk of developing or dying from cancer refers to the chance a person has, over the course of their lifetime (from birth to death), of being diagnosed with or dying from cancer. These risk estimates are one way to measure of how widespread cancer is in the United States.

The following tables list lifetime risks of developing and dying from certain cancers for men and women in the United States. The information is from the National Cancer Institute’s Surveillance Epidemiology and End Results (SEER) database, and is based on incidence and mortality data in the US from 2017 through 2019, the most recent years for which data are available.

The risk is expressed both in terms of a percentage and as odds.

  • For example, the risk that a man will develop cancer of the pancreas during his lifetime is 1.7%. This means he has about 1 chance in 59 of developing pancreatic cancer (100/1.7 = 59).
  • Put another way, 1 out of every 59 men in the United States will develop pancreatic cancer during his lifetime.

These numbers are average risks for the overall US population. Your risk may be higher or lower than these numbers, depending on your particular risk factors for each type of cancer.

Males

 

Risk of developing

Risk of dying from

 

%

1 in

%

1 in

Any cancer

40.9

2

20.2

5

Bladder (includes in situ)

3.86

28

0.9

111

Brain and nervous system

0.7

147

0.5

189

Breast

0.1

727

<0.1

3,312

Colon and rectum

4.3

23

1.7

578

Esophagus

0.8

128

0.7

138

Hodgkin lymphoma

0.2

435

<0.1

2,899

Kidney and renal pelvis

2.3

44

0.6

177

Larynx (voice box)

0.5

200

0.2

570

Leukemia

1.8

55

0.9

108

Liver and bile duct

1.5

66

1.0

96

Lung and bronchus

6.2

16

4.7

21

Melanoma of the skin*

3.5

28

0.4

240

Multiple myeloma

0.9

106

0.5

219

Non-Hodgkin lymphoma

2.3

43

0.8

128

Oral cavity and pharynx
(mouth and throat)

1.7

60

0.4

240

Pancreas

1.7

59

1.4

71

Prostate

12.6

8

2.4

41

Stomach

1.0

102

0.4

246

Testicles

0.4

246

<0.1

4,966

Thyroid

0.6

155

0.1

1,706

Females

 

Risk of developing

Risk of dying from

 

%

1 in

%

1 in

Any cancer

39.1

3

17.7

6

Bladder (includes in situ)

1.1

91

0.3

294

Brain and nervous system

0.5

188

0.4

241

Breast

12.9

8

2.5

39

Cervix

0.7

153

0.2

466

Colon and rectum

3.9

26

1.6

63

Esophagus

0.2

439

0.2

524

Hodgkin lymphoma

0.2

532

<0.1

3,819

Kidney and renal pelvis

1.3

75

0.3

316

Larynx (voice box)

0.1

852

<0.1

2,346

Leukemia

1.3

78

0.7

152

Liver and bile duct

0.7

146

0.6

181

Lung and bronchus

5.8

17

4.0

25

Melanoma of the skin*

2.4

41

0.2

465

Multiple myeloma

0.7

134

0.4

275

Non-Hodgkin lymphoma

1.9

53

0.6

167

Oral cavity and pharynx
(mouth and throat)

0.7

141

0.2

537

Ovary

1.1

88

0.8

123

Pancreas

1.6

61

1.4

73

Stomach

0.6

157

0.3

359

Thyroid

1.7

59

0.1

1,440

Uterus

3.1

33

0.7

152

*The risk numbers for melanoma are for non-Hispanic White individuals. The risk among people of other races/ethnicities is likely to be lower.

The American Cancer Society medical and editorial content team

Our team is made up of doctors and oncology certified nurses with deep knowledge of cancer care as well as journalists, editors, and translators with extensive experience in medical writing.

American Cancer Society. Lifetime Probability of Developing and Dying from Cancer, 2017-2019 (Cancer Facts & Figures 2023 Supplemental Data). 2023. Accessed at https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2023/sd4-lifetime-probability-2023-cff.pdf on January 12, 2023.

Last Revised: January 12, 2023